Publications

Functional connectivity-based classification of rapid eye movement sleep behavior disorder. Matsushima T, Yoshinaga K, Wakasugi N, Togo H, Hanakawa T, Japan Parkinson's Progression Markers Initiative (J-PPMI) study group. Sleep Med 115:5-13, 2024. 

  Reduced pineal volume may be associated with amyloid pathology and not with putative Lewy body pathology Matsuoka T, Oya N, Narumoto J, Morii-Kitani F, Niwa F, Mizuno T, Akazawa K, Yamada K, Abe M, Takano H, Wakasugi N, Shima A, Sawamoto N, Ito H, Toda W, Hanakawa T, Parkinson’s and Alzheimer’s disease Dimensional Neuroimaging Initiative: Comparison in pineal volume between Alzheimer’s and Parkinson’s disease spectrums. J Neurol Neurosurg Psychiat doi: 10.1136/jnnp-2023-332252

Macrostructural Cerebellar Neuroplasticity Correlates With Motor Recovery After Stroke .Hanakawa T, Hotta F, Nakamura T, Shindo K, Ushiba N, Hirosawa M, Yamazaki Y, Sato Y, Takai S, Mizuno K, Liu M: Neurorehab Neural Repair 37(11-12):775-785, 2023 Dec. doi: 10.1177/15459683231207356

Analysis of abnormal posture in patients with Parkinson's disease using a computational model considering muscle tones. Omura Y, Togo H, Kaminishi K, Hasegawa T, Chiba R, Yozu A, Takakusaki K, Abe M, Takahashi Y, Hanakawa T, Ota J: Front Comp Neurosci 17:1218707, 2023.  

 Identifying and reverting the adverse effects of white matter hyperintensities on cortical surface analyses Oi Y, Hirose M, Togo H, Yoshinaga K, Akasaka T, Oakada T, Aso T, Takahashi R, Glasser MF, Hayashi T, Hanakawa T: Neuroimage 281:120377, 2023.

Contribution of amyloid and putative Lewy body pathologies in neuropsychiatric symptoms Matsuoka T, Oya N, Narumoto J, Morii-Kitani F, Niwa F, Mizuno T, Akazawa K, Yamada K, Abe M, Takano H, Wakasugi N, Shima A, Sawamoto N, Ito H, Toda W, Hanakawa T, Parkinson’s and Alzheimer’s disease Dimensional Neuroimaging Initiative: Int J Geriatr Psychiatry 38(9):e5993, 2023.

  Changes in functional brain activity patterns associated with computer programming learning in novices. Hishikawa T, Yoshinaga K, Togo H, Hongo T, Hanakawa T: Brain Struct Funct 228(7):1691-1701, 2023.

 Analysis of the Relationship Between Muscle Tones and Abnormal Postures in a Computational Model. Omura Y, Togo H, Kaminishi K, Hasegawa T, Chiba R, Yozu A, Takakusaki K, Abe M, Takahashi Y, Hanakawa T, Ota J: Annu Int Conf IEEE Eng Med Biol Soc:1-4, 2023.

 Altered diurnal pattern of interleukin-6 is associated with amygdalar emotional reactivity and depression: a modulating role of gene-stressor interaction. Hakamata Y, Hori H, Mizukami S, Izawa S, Yoshida F, Moriguchi Y, Hanakawa T, Inoue Y, Tagaya H: Front Psychiat 14:1196235, 2023.

  Simulating developmental diversity: Impact of neural stochasticity on atypical flexibility and hierarchy  Soda T, Ahmadi A, Tani J, Honda M, Hanakawa T, Yamashita Y: Atypical Development of Flexibility and Hierarchical Representation Induced by Imbalance between Stochastic and Deterministic Neural Dynamics: Bayesian Recurrent Neural Network Modeling. Front Psychiat 14: 1080668, 2023.

  Interactions across emotional, cognitive, and motor networks underlying the freezing of gait. Togo H, Nakamura T, Wakasugi N, Takahashi Y, Hanakawa T: Neuroimage: Clin 37: 103342, 2023.

Structural neuroplasticity in computer programming beginners.Hongo T, Yakou T, Yoshinaga K, Kano T, Miyazaki M, Hanakawa T: Cereb Cortex 33(9): 5375-5381, 2023 April

 Precise motor rhythmicity relies on motor network responsivity. Uehara K, Togo H, Hanakawa T: Cereb Cortex 33(8): 4432-4447, 2023.

Time course of recovery of different motor functions following a reproducible cortical infarction in non-human primates. Kosugi K, Saga Y, Kudo M, Koizumi M, Umeda T, Seki K, :Front Neuology  14:10.3389/fneur.2023.10947 2023 

Perceptual inference, accuracy, and precision in temporal reproduction in schizophrenia.  Ueda N, Tanaka K, Maruo K, Roach N, Sumiyoshi T, Watanabe K,  Hanakawa T. Schizophrenia Research: Cognition. June 2022; 28:100229, doi: https://doi.org/10.1016/j.scog.2021.100229.

Neuroplasticity Caused by Peripheral Proprioceptive Deficits. Shitara H, Ichinose T, Shimoyama D, Sasaki T, Hamano N, Kamiyama M, Tajika T, Yamamoto A, Kobayashi T, Hanakawa T, Tsushima Y, Takagishi K, Chikuda H. Med Sci Sports Exerc. January 2022; 1;54(1):28-37. doi: 10.1249/MSS.0000000000002775. 

A computational model based on corticospinal functional MRI revealed asymmetrically organized motor corticospinal networks in humans. Takasawa  E, Abe M, Chikuda H, Hanakawa T. Communications Biology. July 2022. doi:https://doi.org/10.1038/s42003-022-03615-2 

Increased Gray Matter Volume Induced by Chinese Language Acquisition in Adult Alphabetic Language Speakers.Tu L, Zhou F, Omata K, Li W, Huang R, Gao W, Zhu Z, Li Y, Liu C, Mao M, Zhang S and Hanakawa T. Front Psychol. April 2022. doi:https://doi.org/10.3389/fpsyg.2022.824219

Basal ganglia-cortical connectivity underlies self-regulation of brain oscillations in humans.Kasahara K, Charles S. DaSalla,  Honda M and Hanakawa T. Communications Biology. 16 July 2022. doi:https://doi.org/10.1038/s42003-022-03665-6   

Detection of deviance in Japanese kanji compound words. Egashira Y, Kaga Y, Gunji A, Kita Y , Kimura M, Hironaga N, Takeichi H, Hayashi S, Kaneko Y, Takahashi H, Hanakawa T, Okada T and Inagaki M. Front Hum. 15 August 2022. doi:https://doi.org/10.3389/fnhum.2022.913945 

Idiopathic rapid eye movement sleep behavior disorder in Japan: An observational study. Nishikawa N,Murata M,Hatano T,Mukai Y,Saitoh Y,Sakamoto T,Hanakawa T,Kamei Y,Tachimori H,Hatano K,Matsuda H,Taruno Y,Sawamoto N,Kajiyama Y,Ikenaka k,Kawabata K,Nakamura T,Iwaki H and Takahashi R. Parkinson Relat Disord. 13 September 2022. doi:https://doi.org/10.1016/j.parkreldis. 2022.08.011 

Precise motor rhythmicity relies on motor network responsivity. Uehara K, Togo H, Hanakawa T. National Library on Medicine. 11 Oct 2022. doi:10.1093/cercor/bhac353

 Structural neuroplasticity in computer programming beginners.Hongo T, Yakou T, Yoshinaga K, Kano T, Miyazaki M, Hanakawa T. National Library on Medicine. 29 Oct 2022. bhac425.doi: 10.1093/cercor/bhac425.

Temporal dynamics of the sensorimotor convergence underlying voluntary limb movement.Umeda T, Isa T, Nishimura Y. PNAS. 2022 Nov 29;119(48):e2208353119. doi: 10.1073/pnas.2208353119. Epub 2022 Nov 21.

International Data Governance for Neuroscience. Eke D, Bernard A, Bjaalie JG, Chavarriaga R, Hanakawa T, Hannan AJ, Hill SL, Martone M, McMahon A, Ruebel O, Thiels F, Pestilli F. Neuron. December 2021. doi: https://doi.org/10.1016/j.neuron.2021.11.017

It Is Time to Study Overlapping Molecular and Circuit Pathophysiologies in Alzheimer’s and Lewy Body Disease Spectra. Wakasugi N, Hanakawa T. Front. Syst. Neurosci. November 2021. doi: 10.3389/fnsys.2021.777706

Is Generalized and Segmental Dystonia Accompanied by Impairments in the Dopaminergic System? Ikezawa J, Yokochi F, Okiyama R, Kumada S, Tojima M, Kamiyama T, Hanakawa T, Matsuda H, Tanaka F, Nakata Y, Isozaki E. Front. Neuro. November 2021. doi: 10.3389/fneur.2021.751434     

Don’t think, feel: basal ganglia-cortical connectivity underlies self-regulation of brain oscillations in humans. Kasahara K, DaSalla CS, Honda M, Hanakawa T. bioRxiv. July 2021. doi: https://doi.org/10.1101/2021.07.19.453008

Wrist and finger motor representations embedded in the cerebral and cerebellar resting-state activation. Kusano T, Kurashige H, Nambu I, Moriguchi Y, Hanakawa T, Wada Y, Osu R. Brain Struct Funct. July 2021; 226:2307–2319. doi: 10.1007/s00429-021-02330-8

Correlation between the brain activity with gait Imagery and gait performance in adults with Parkinson's disease: a data set. Nishida D, Mizuno K, Yamada E, Tsuji T, Hanakawa T, Liu M. Data Brief. Jun 2021; 36:106993. doi: 10.1016/j.dib.2021.106993

Aberrant cerebello-cortical connectivity in pianists with focal task-specific dystonia. Kita K, Furuya S, Osu R, Sakamoto T, Hanakawa T. Cerebral Cortex. May 2021; 31(10):4853–4863. https://doi.org/10.1093/cercor/bhab127

Childhood trauma affects autobiographical memory deficit through basal cortisol and prefrontal-extrastriate functional connectivity. Hakamata Y, Izawa S, Mizukami S, Moriguchi Y, Hori H, Matsumoto N, Hanakawa T, Inoue Y, Tagaya H. Psychoneuroendocrinology. May 2021; 127:105172. https://doi.org/10.1016/j.psyneuen.2021.105172.2021

Prefrontal network dysfunctions in rapid eye movement sleep behavior disorder. Wakasugi N, Togo H, Mukai Y, Nishikawa N, Murata M, Takahashi Y, Matsuda H, Hanakawa T. Parkinson Relat Disord. April 2021; 85:72-77. https://doi.org/10.1016/j.parkreldis.2021.03.005

Brain/MINDS beyond human brain MRI group: Brain/MINDS beyond human brain MRI study: Multi-site harmonization for brain disorders throughout the lifespan. Koike S, Tanaka SC, Okada T, Aso T, Asano M, Maikusa N, Morita K, Okada N, Fukunaga M, Uematsu A Togo H, Miyazaki A, Murata K, Urushibata Y, Autio J, Ose T, Yosihmoto J, Araki T, Glasser MF, Maruyama M, Sadato N, Kawato M, Kasai K, Okamoto Y, van Essen D, Hanakawa T, Hayashi T, Neuroimage: Clinical. March 2021; 30:102600. https://doi.org/10.1016/j.nicl.2021.102600

Frequency- and area-specific entrainment of intrinsic cortical oscillations by repetitive transcranial magnetic stimulation. Okazaki Y, Nakagawa Y, Mizuno Y, Hanakawa T, Kitajo K. Front Hum Neurosci. March 2021. https://doi.org/10.3389/fnhum.2021.608947

The neural correlates of gait improvement by rhythmic sound stimulation in adults with Parkinson's disease – A functional magnetic resonance imaging study. Nishida D, Mizuno K, Yamada E, Hanakawa T, Liu M, Tsuji T. Parkinson Relat Disord. March 2021; 84:91-97. doi: 10.1016/j.parkreldis.2021.02.010

Age of acquisition of mandarin modulates cortical thickness in high-proficient Cantonese-Mandarin bidialectals. Tu L, Niu M, Pan X, Hanakawa T, Liu X, Lu Z, Gao W, Ouyang D, Zhang M, Li S, Jiang B, Huang R. J Psycholinguist Res. July 2021; 50(4):723-736. doi: 10.1007/s10936-020-09716-5

Electrophysiological effects of transcranial direct current stimulation on neural activity in the rat cortex. Tanaka T, Isomura Y, Kobayashi K, Hanakawa T, Tanaka S, Honda M. Front Neurosci. June 2020. https://doi.org/10.3389/fnins.2020.00495

Comparison of phase synchronization measures for identifying stimulus-induced functional connectivity in human magnetoencephalographic and simulated data. Yoshinaga K, Matsuhashi M, Mima T, Fukuyama H, Takahashi R, Hanakawa T, Ikeda A. Front Neurosci. June 2020. https://doi.org/10.3389/fnins.2020.00648

Plastic frontal pole cortex structure related to individual persistence for goal achievement. Hosoda C, Tsujimoto S, Tatekawa M, Honda M, Osu R, Hanakawa T.  Commun Biol 3. April 2020; 194. https://doi.org/10.1038/s42003-020-0930-4

Timing of phase-amplitude coupling is essential for neuronal and functional maturation in adolescents. Ohki T, Matsuda T, Gunji A, Takei Y, Sakuma R, Kaneko Y, Inagaki M, Hanakawa T, Ueda K, Fukuda M, Hiraki K. Brain Behav. April 2020. https://doi.org/10.1002/brb3.1635

Assessment and rating of motor cerebellar ataxias with Kinect v2 depth sensor: Extending our appraisal. Honda T, Mitoma H, Yoshida H, Bando K, Terashi H, Taguchi T, Miyata Y, S, Hanakawa T, Aizawa H, Kondo T, Mizusawa H, Manto M, Kakei S. Front Neurol. March 2020; 11:179. https://doi.org/10.3389/fneur.2020.00179

Basolateral amygdala connectivity with subgenual anterior cingulate cortex represents enhanced fear-related memory encoding in humans. Hakamata Y, Mizukami S, Izawa S, Mizukami S, Moriguchi Y, Hori H, Kim Y, Hanakawa T, Inoue Y, Tagaya H. Biol Psychiatry Cogn Neurosci Neuroimaging. March 2020; 5(3):301-310. https://doi.org/10.1016/j.bpsc.2019.11.008

Revealing relationship among cognitive functions using functional connectivity and large-scale meta-analysis database. Kurashige H, Yamashita Y, Osu R, Otaka Y, Hanakawa T, Honda M, Kawabata H. Front Human Neurosci. January 2020. https://doi.org/10.3389/fnhum.2019.00457

花川 隆：PADNI研究. Dementia Japan 35:39-44, 2021 

花川 隆：イメージングバイオマーカーとしての脳機能結合．脳神経内科 92(2): 206-210, 2020. 

花川隆：講演「MRIを中核技術とするマルチモーダルイメージングによる中枢神経機能の解明」第46回日本脳神経CI学会総会@千葉幕張メッセ.2023.1.20

花川隆：講演「高齢者神経画像データベースPADNIから得られる知見」第15回名古屋分子標的イメージングセミナー@web開催.2023.2.9

花川隆：講演「神経科学研究のススメ」脳科学クラスター　ミニリトリート@徳島大学病院　日亜メディカルホール.2023.2.21　講演の様子： 徳島大学脳神経外科サイト

梅田達也：講演「Spinal reflex representation in the primary motor cortex　一次運動野は脊髄反射をコードする 」第100回日本生理学会大会＠国立京都国際会館　2023.3.15

梅田達也：講演「霊長類を用いた運動－体性感覚連関のシステム神経科学研究 」第3回光散乱透視学セミナー＠神戸大学　2023.3.31

花川隆：講演「神経変性疾患の多次元神経情報計測に基づく神経機能の制御戦略 」第31回日本医学会総会　柱2-11 脳情報の解読に基づく脳神経疾患の治療戦略.@東京国際フォーラム 2023.04.22

花川隆：ポスター発表「Parkinson’s and Alzheimer’s disease Dimensional Neuroimaging InitiativeHarmonization of dopamine transporter SPECT imaging improves segregation between patients with Parkinson’s disease and healthy elderlies in multicentre cohort studies.」第64回日本神経学会学術大会, @幕張メッセ　2023.06.02  Noritaka Wakasugi, Harumasa Takano, Mitsunari Abe, Nobukatsu Sawamoto, Toshiya Murai, Toshiki Mizuno, Teruyuki Matsuoka, Ryo Yamakuni, Hirooki Yabe, Hiroshi Matsuda, Takashi Hanakawa

花川隆：学生・研修医優秀口演賞候補セッション「安静時機能的MRIを用いたパーキンソン病における不安関連ネットワーク変容の解明」第64回日本神経学会学術大会@幕張メッセ　2023.06.03　浅田怜央、吉永健二、西田聖、澤本伸克、花川隆,, 幕張メッセ 

花川隆：講演「変わる脳（変わらない私？）」 世界脳週間2023京都講演会@東山高校　2023.7.12

花川隆：講演「MRI・PETの高度化、高精度脳機能イメージングの創薬活用 」日本製薬工業協会・研究開発委員会セミナー @京大　2023.8.7

花川隆：特別講演「学習・機能回復を支える神経“弾塑性”」第21回日本神経理学療法学会学術大会 @パシフィコ横浜  2023.9.10

花川隆：講演「神経画像コホート研究によるRBDの病態理解と神経変性疾患発症予測の展望」日本睡眠学会第45回定期学術集会・第30回日本時間生物学会学術大会合同大会 @パシフィコ横浜 2023.9.15

花川隆：講演「Current trends in somatosensory research」「Comprehensive neuroimaging to gain new insight into brain pathophysiology of Parkinson's disease and related disorders 」日本臨床神経生理学会第53回学術大会/第60回技術講習会 @福岡国際会議場  2023.12.2

花川隆：講演「BCI制御に関わる神経基盤のマルチモーダル計測」第32回実社会におけるマルチモーダル脳情報応用技術研究会@オンライン開催.2022.1.24

花川隆：講演「高齢者神経変性疾患の病態理解を目指したマルチモーダルイメージング データベースの構築研究」第15回関西脳核医学研究会@オンライン開催.2022.3.5

花川隆：講演「日本の医療分野における情報化：DxとAI」第63回日本神経学会学術大会@東京国際フォーラム.2022.5.20

花川隆：講演「MRIを軸にした多モーダル脳計測の最前線」第34回東京臨床脳画像解析研究会@オンライン開催.2022.6.8

梅田達也：講演「白質病変が健常高齢者の皮質表面解析に及ぼす影響と改善のための新手法　The adverse effects of white matter lesions on cortical surface analysis in the healthy aged adults: A method proposed for improvement 」NEURO2022　第45回日本神経科学大会@沖縄コンベンションセンター2022.6.30

梅田達也：講演「随意運動において下行性入力と感覚フィードバック信号は連続的に筋活動生成に寄与する　Sequential contribution of descending drive and afferent feedback to muscle activity during voluntary limb movements 」 NEURO2022　第45回日本神経科学大会@沖縄コンベンションセンター2022.7.1

花川隆：講演「パーキンソン病の病態における淡蒼球の役割」13回 お茶の水 Neuroimaging Conference– ONIC –@泉ガーデンタワー42F・住友会館.2022.8.26

花川隆：講演「MRI技術を情報のハブとする多モーダル脳構造・機能計測」第50回日本磁気共鳴医学会大会@名古屋国際会議場.2022.9.10

花川隆：講演　北野病院脳神経外科60周年記念の会@大阪帝国ホテル.2022.10.29

花川隆：講演「ブレインマシンインターフェイスの臨床応用の展望」京都大原記念病院グループ京都大学神経機能回復・再生医学講座合同シンポジウム@京都大学基礎医学記念講堂.2022.11.12

花川隆：講演「精神・神経疾患 MRI コホートとデータベースの融合研究プラットフォームに寄せる期待」三施設連携研究協定締結キックオフ・シンポジウム＠京都大学稲盛記念ホール.2022.12.6

花川隆：講演「画像から読み解く局所性ジストニアの起源―音楽家のジストニアを中心に―」第62回日本神経学会学術大会@国立京都国際会館.2021.5.19

花川 隆：講演「神経疾患のコネクトーム解析 ～パーキンソン病関連疾患を中心に～」第60回亀山正邦記念神経懇話会@オンライン開催.2021.6.12

花川 隆： 講演「脳情報の解読」徳島市立高校理数科セミナー＠芝蘭会館. 2021.07.29.

花川 隆：講演「統合的アプローチによる神経疾患の脳ネットワーク病態解明」第17回新潟県脳機能解析研究会@オンライン開催.2021.8.19

花川 隆：講演「シンポジウム神経変性疾患の画像診断トピックス」第39回日本神経治療学会学術集会@三重県総合文化センター.2021.10.30

花川隆：講演「安静時機能結合 fMRI は何を測定しているか？」第51回日本臨床神経生理学会学術大会@仙台国際センター.2021.12.16